Nielsen Lab

Professor
Jens Nielsen

Department of Biology and Biological Engineering,
Chalmers University of Technology,
Kemivägen 10, SE-412 96 Göteborg, Sweden

Phone:
+46 (0)31 772 3804
Fax: +46(0)31 772 3801
E-mail: nielsenj [at] chalmers.se
Office: Room 3044

 

Our research focus is on systems biology of metabolism. The yeast Saccharomyces cerevisiae is our key organism for experimental research, but we also have experimental research on Aspergilli oryzae. Interview about some of our work

Our research activities fall in three areas:

  • Studying regulatory pathways that are conserved in the Eukaryal kingdom such as the Snf1/AMPK pathway, the Tor1/mTOR pathway, protein folding, secretion and degradation and regulation of lipid biosynthesis and degradation.
  • Developing efficient cell factories (yeast and Aspergilli) for sustainable production of fuels and chemicals. We are looking into both the production of high-value chemicals such as isoprenoids that can be used as fine chemicals, commodity chemicals that can be used as feedstocks in the chemical industry for polymer production, and novel advanced biofuels.
  • Developing metabolic models for Eukaryal cells, including rodent and human cells, and using these models as scaffolds for analysis of omics data with the objective to understand global responses to nutrient and disease. Experimental work is carried out in collaboration with other research groups.

Several of our research activities are part of the Novo Nordisk Foundation Center for Biosustainability. See www.biosustain.dtu.dk and video for more information

 

Hohmann Lab Larsson Lab Nielsen Lab Mijakovic Lab
Petranovic Lab Engqvist Lab    
   

Latest News

Jens Nielsen's research covered in GP (Göteborgs-Posten)

Leif Väremo’s thesis entitled “Systems Biology of Type 2 Diabetes in Skeletal Muscle” was selected as the best preclinical thesis by the Swedish Diabetes Association.

Jens Nielsen was appointed Honorary Professor at East China University of Science and Technology, Shanghai, China

Jens Nielsen was appointed as Adjunct Professor at Jiangnan University, Wuxi, China

Through sequencing 10 penicillia genome SysBio identified a large number of new secondary metabolite biosynthetic gene clusters were identified. The study was published in Nature Microbiology and featured in Cosmos Magazine.

Paper published in Nature Chemical Biology about engineering the yeast fatty acid synthase for production of short chain fatty acids by yeast was covered by more than 30 newspapers around the world



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