Nielsen Lab

Jens Nielsen

Department of Biology and Biological Engineering,
Chalmers University of Technology,
Kemivägen 10, SE-412 96 Göteborg, Sweden

+46 (0)31 772 3804
Fax: +46(0)31 772 3801
E-mail: nielsenj [at]
Office: Room 3044


Our research focus is on systems biology of metabolism. The yeast Saccharomyces cerevisiae is our key organism for experimental research, but we also have experimental research on Aspergilli oryzae. Interview about some of our work

Our research activities fall in three areas:

  • Studying regulatory pathways that are conserved in the Eukaryal kingdom such as the Snf1/AMPK pathway, the Tor1/mTOR pathway, protein folding, secretion and degradation and regulation of lipid biosynthesis and degradation.
  • Developing efficient cell factories (yeast and Aspergilli) for sustainable production of fuels and chemicals. We are looking into both the production of high-value chemicals such as isoprenoids that can be used as fine chemicals, commodity chemicals that can be used as feedstocks in the chemical industry for polymer production, and novel advanced biofuels.
  • Developing metabolic models for Eukaryal cells, including rodent and human cells, and using these models as scaffolds for analysis of omics data with the objective to understand global responses to nutrient and disease. Experimental work is carried out in collaboration with other research groups.

Several of our research activities are part of the Novo Nordisk Foundation Center for Biosustainability. See and video for more information


Hohmann Lab Larsson Lab Nielsen Lab Mijakovic Lab
Petranovic Lab      

Latest News

Paper published in Nature Chemical Biology about engineering the yeast fatty acid synthase for production of short chain fatty acids by yeast was covered by more than 30 newspapers around the world

Youngjin Zhou was given a young scholar award at the International Conference on Metabolic Science, Shanghai, based on his excellent oral presentation

SysBio poster presented by former post doc Guodong Liu wins award at the 13th International Symposium on Genetics of Industrial Microorganisms in Wuhan, China

Jens Nielsen talks about microbiota for STAT, a Boston Globe Media magazine.

Nielsen and Keasling review in Cell

Jens Nielsen about mentorship in journal Cell

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