Assistant professor Dina Petranovic, PhD Department of Chemical and Biological Engineering, Chalmers University of Technology, Kemivägen 10, SE-412 96 Göteborg, Sweden Phone: +46(0)31 772 3831 Fax: +46(0)31 772 3801 E-mail: dina.petranovic [at] chalmers.se Office: Room 3054A     Education and degrees 1999 M.Sc. in Molecular Biology, Faculty of Science and Mathematics, University of Zagreb, Croatia 2004 Ph.D. in Molecular Microbiology, University Paris XI, France Employments 1997-1998 Teaching Assistant, Faculty of Science and Mathematics, University of Zagreb, Croatia 2000-2004 PhD student, University Paris XI and INRA, Paris, France 2004-2007 Assistant Professor, Molecular Physiology and Genetics, Technical University of Denmark, Lyngby, Denmark 2007-2008 Project Manager, Center for Microbial Biotechnology, Technical University of Denmark, Lyngby, Denmark 2008- Assistant Professor, Department of Chemical and Biological Engineering, Chalmers Academic Experience 2004- reviewer for several international peer-reviewed scientific journals 2009 expert for evaluation of proposals for the French National Research Agency (ANR) Publications 2001 Petranović M, Zahradka K, Zahradka D, Petranović D, Nagy B, Salaj-Smic E, Petranović D. Genetic evidence that the elevated levels of Escherichia coli helicase II antagonize recombinational DNA repair. Biochimie. 83:1041-7 2004 Petranovic D, Mijakovic I. Photometric assay for measuring the intracellular concentration of branched-chain amino acids in bacteria. J Microbiol Methods. 01:133-6   Petranovic D, Guédon E, Sperandio B, Delorme C, Ehrlich D, Renault P. Intracellular effectors regulating the activity of the Lactococcus lactis CodY pleiotropic transcription regulator. Mol Microbiol. 2:613-21   Mijakovic I, Petranovic D, Deutscher J. How tyrosine phosphorylation affects the UDP-glucose dehydrogenase activity of Bacillus subtilis YwqF. J Mol Microbiol Biotechnol. 1:19-25 2005 Mijakovic I, Musumeci L, Tautz L, Petranovic D, Edwards RA, Jensen PR, Mustelin T, Deutscher J, Bottini N. In vitro characterization of the Bacillus subtilis protein tyrosine phosphatase YwqE. J Bacteriol. 10:3384-90   Mijakovic I, Petranovic D, Jensen PR. Tunable promoters in systems biology. Curr Opin Biotechnol. 3:329-35   Mijakovic I, Petranovic D, Bottini N, Deutscher J, Ruhdal Jensen P. Protein-tyrosine phosphorylation in Bacillus subtilis. J Mol Microbiol Biotechnol. 9 (3-4):189-97 2006 Mijakovic I, Petranovic D, Macek B, Cepo T, Mann M, Davies J, Jensen PR, Vujaklija D. Bacterial single-stranded DNA-binding proteins are phosphorylated on tyrosine. Nucleic Acids Res. 5:1588-96 2007 Petranovic D, Michelsen O, Zahradka K, Silva C, Petranovic M, Jensen PR, Mijakovic I. Bacillus subtilis strain deficient for the protein-tyrosine kinase PtkA exhibits impaired DNA replication. Mol Microbiol. 6:1797-805 2008 Koebmann B, Blank LM, Solem C, Petranovic D, Nielsen LK, Jensen PR. Increased biomass yield of Lactococcus lactis during energetically limited growth and respiratory conditions Biotechnol Appl Biochem. 50(Pt 1):25-33   Soufi B, Jers C, Hansen ME, Petranovic D, Mijakovic I. Insights from site-specific phosphoproteomics in bacteria. Biochim Biophys Acta. 1:186-92   Soufi B, Gnad F, Jensen PR, Petranovic D, Mann M, Mijakovic I, Macek B. The Ser/Thr/Tyr phosphoproteome of Lactococcus lactis IL1403 reveals multiply phosphorylated proteins. Proteomics. 17:3486-93   Petranovic D, Nielsen J. Can yeast systems biology contribute to the understanding of human disease? Trends Biotechnol. 11:584-90   Herrgård MJ, Swainston N, Dobson P, Dunn WB, Arga KY, Arvas M, Blüthgen N, Borger S, Costenoble R, Heinemann M, Hucka M, Le Novère N, Li P, Liebermeister W, Mo ML, Oliveira AP, Petranovic D, Pettifer S, Simeonidis E, Smallbone K, Spasić I, Weichart D, Brent R, Broomhead DS, Westerhoff HV, Kirdar B, Penttilä M, Klipp E, Palsson BØ, Sauer U, Oliver SG, Mendes P, Nielsen J, Kell DB. A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology. Nat Biotechnol. 10:1155-60 2009 Petranovic D, Grangeasse C, Macek B, Abdillatef M, Gueguen-Chaignon V, Nessler S, Deutscher J, Mijakovic I. Activation of Bacillus subtilis Ugd by the BY-Kinase PtkA Proceeds via Phosphorylation of Its Residue Tyrosine 70. J Mol Microbiol Biotechnol. 17(2):83-9.   Petranovic D & Vemuri GN Impact of yeast systems biology on industrial biotechnology. J Biotechnol. 144(3):204-11. Teaching and Tutoring Experience 1997- teaching at undergraduate level Biochemistry, Molecular and Cell Biology, Molecular Genetics and Molecular Biotechnology at different Universities (University of Zagreb, Technical University of Denmark and Chalmers University)   I supervised two M.Sc. students, 3 PhD students and 3 post-docs and was involved in co-supervision of few other students and training of 2  technicians. Grants, Awards and Prizes 2009 Wallenberg Foundation Travel Grant Organization and Management Besides managing my own scientific projects I have been working as project manager for several big projects which are coordinated by our group: since 2007 YSBN (EU-funded project in the 6th framework) and NordForsk and since 2008 SYSINBIO and FUtureSysBio (EU-funded project in the 7th framework). I was in the organizing committee of the International Conference for Systems Biology ICSB2008 (Gothenburg, Sweden), Conference on Systems Biology of Microorganisms 2010 (Paris, France) and Gothenburg Life Science Conference XI (2010). Personal text I am coming from the background of molecular microbiology and have been working mainly on gene regulation (CodY) and protein phosphorylation (PY) in G+ bacteria (Lactococcus lactis, Bacillus subtilis). In the last few years I became interested in using unicellular Eukarya such as yeast Saccharomyces cerevisiae as a model organism for study of complex cellular functions, such as proteome maintenance, ageing and apoptosis.