Assistant professor Goutham Vemuri, PhD Department of Chemical and Biological Engineering, Chalmers University of Technology, Kemivägen 10, SE-412 96 Göteborg, Sweden Phone: +46(0)31 772 3882 Fax: +46(0)31 772 3801 E-mail: goutham [at] chalmers.se Office: Room 3054B     Education and degrees 1998 B.Techn. (Hons.), Chemical Engineering, Indian Institute of Technology, Kharagpur, India 2001 MS in Biological Engineering, University of Georgia, Athens, GA, USA 2007 PhD in Biological Engineering, University of Georgia, Athens, GA USA Employments 1998-2001 Research Assistant, University of Georgia, Athens, GA, USA 2002 Bioprocess Engineer, Shire Biologics, Northboro, MA, USA 2003-2007 University-wide Fellow, University of Georgia, Athens, GA, USA 2007-2008 Hans Christian Ørstad Post-doctoral fellow, Denmark Technical University, Denmark 2008- Assistant Professor, Department of Chemical and Biological Engineering, Chalmers Publications, Patents & Presentations Publications 2002 G.N. Vemuri, M.A. Eiteman, E. Altman. Succinate production in dual-phase Escherichia coli fermentations depends on the time of transition from aerobic to anaerobic conditions. J.  Ind. Microbiol. Biotechnol. 28:325-332   G N. Vemuri, M.A. Eiteman, E. Altman. Effects of growth mode and pyruvate carboxylase on succinic acid production by metabolically engineered strains of Escherichia coli. Appl. Environ. Microbiol. 68:1715-1727 2005 G.N. Vemuri, T.A. Minning, E. Altman, M.A. Eiteman. Physiological response of central metabolism in Escherichia coli to deletion of pyruvate oxidase and introduction of heterologous pyruvate carboxylase. Biotechnol. Bioeng.  90:64-76   G.N. Vemuri, A.A. Aristidou. Metabolic engineering in the omics era: elucidating and modulating regulatory networks. Microbiol. Mol. Biol. Rev. 69:197-216 2006 G.N. Vemuri, M.A. Eiteman, E. Altman. Increased recombinant protein production in Escherichia coli strains with overexpressed water-forming NADH oxidase and a deleted ArcA regulatory protein. Biotechnol. Bioeng. 94:538-542   G.N. Vemuri, E. Altman, D. Sangurdekar, A.B. Khodursky, M.A. Eiteman. Overflow metabolism in Escherichia coli during steady-state growth: Transcriptional regulation and the effect of redox. Appl. Env. Microbiol. 72:3653-3661 2007 G.N. Vemuri, M.A. Eiteman, J.E. McEwen, L. Olsson, J. Nielsen. Increasing NADH oxidation reduces overflow metabolism in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci., USA 104:2402-2407 2009 Hou, J., G.N. Vemuri, X. Bao, L. Olsson. Impact of overexpressing NADH kinase on glucose and xylose metabolism in recombinant xylose-utilizing Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol.82:xx-xx Book Chapters 2009 G.N. Vemuri, J. Nielsen. "Yeast as a prototype for systems biology" in Systems Biology and Synthetic Biology, P. Fu, M. Latterich and S. Panke eds, John Wiley Popular Science articles 2008 G.N. Vemuri, J. Nielsen. 2008. Systems Biology: Is the hope worth the hype? SIM News Patents G.N. Vemuri, M.A. Eiteman, E. Altman, Reduced overflow metabolism and methods of use. US Pat Appl. 20070249018 Talks   2002 G.N. Vemuri, M.A. Eiteman, E. Altman. Effect of time of transition during dual-phase Escherichia coli fermentations on succinic acid production. Annual Meeting of Society for Industrial Microbiology, Philadelphia, PA 2005 G.N. Vemuri et al. Overcoming overflow metabolism in industrial strains by redox engineering, Annual meeting of the Society for Industrial Microbiology, Chicago, IL   G.N. Vemuri, J. Nielsen. Centre for Microbial Biotechnology: A brief overview. Indo-Danish collaborative workshop, Odense, Denmark 2006 G.N. Vemuri et al. Metabolic Engineering for Improvement of glycopeptide production in Amycolatopsis balhimycina. Danish Conference on Molecular Biology and Biotechnology, Vejle, Denmark 2008 G.N. Vemuri et al. Genome level enquiry into adaptive evolution. Annual meeting of Society for Industrial Microbiology, San Diego, CA   G. N. Vemuri, et al. Why does yeast make ethanol? International Study Group on Systems Biology, Helsingør, Denmark   G.N. Vemuri et al. Bakers yeast as a model for studying metabolic disorders. Yeast Systems Biology Workshop, International Conference on Systems Biology, Göteborg   G.N. Vemuri et al. Rational vs combinatorial approaches to metabolic engineering. Metabolic Engineering VII, Puerto Vallarta, Mexico Poster Presentations 2002 M. A. Eiteman, G. N. Vemuri, A. Tomar, E. Altman. Metabolic engineering of anaplerotic reactions for succinic acid and pyruvic acid production. 24th Symposium on Biotechnology for Fuels and Chemicals, Gatlinburg, Tennessee   M. A. Eiteman, E. Altman, G. N. Vemuri. Dual-phase fermentation of Escherichia coli for the production of succinic acid. Metabolic Engineering 4, Barga, Italy 2003 G.N. Vemuri, T.A. Minning, M.A. Eiteman, E. Altman. Physiological consequences of genetic manipulations at the pyruvate branch point of Escherichia coli. Annual Meeting of Society for Industrial Microbiology, Minneapolis, MN 2004 G.N. Vemuri, E. Altman, M.A. Eiteman. Physiological changes in Escherichia coli associated with altered intracellular NADH concentration as a function of growth rate. Annual Meeting of Society for Industrial Microbiology, Anaheim, CA   G.N. Vemuri, E. Altman, M.A. Eiteman. Effect of redox on overflow metabolism in Escherichia coli. Metabolic Engineering: From genome to product., Lake Tahoe, CA 2005 G.N. Vemuri, M. A. Eiteman, E. Altman. Pyruvate redirection and redox engineering affects overflow metabolism in Escherichia coli,” Institute of Biological Engineering, Athens, Georgia   G.N. Vemuri, M. A. Eiteman, E. Altman. Pyruvate redirection and redox engineering affects overflow metabolism in Escherichia coli,” American Chemical Society National Meeting, San Diego   G.N. Vemuri et al. Revisiting overflow metabolism using global analyses. Society for Industrial Microbiology, Chicago, IL 2006 J. Thykær, A.E. Lantz, G.N. Vemuri, et al. Amycolatopsis balhimycina, a potential cell factory for glycopeptides production? 10th International Symposium on Genetics of Industrial Microorganisms, Prague, Czech Republic   A.E. Lantz, J.Thykær, W. Vongsangnak, G.N. Vemuri, J. Förster and J. Nielsen. Metabolic engineering for improvement of glycopeptide production in Amycolatopsis balhimycina. Metabolic Engineering VI, Noordwijkerhout, The Netherlands   G.N. Vemuri, J. Nielsen, L. Olsson. Metabolic responses to redox perturbations in Saccharomyces cerevisiae. Metabolic Engineering VI, Noordwijkerhout, The Netherlands Teaching and Tutoring Experience 2000 Computer applications in Engineering, Athens, GA, USA 2002 Engineering and Design of Biological Processes, Athens, GA, USA 2005 Metabolic Engineering and Functional Genomics, DTU, Denmark 2006 Metabolic Engineering and Functional Genomics, DTU, Denmark   Training course in Systems Biology, KMUTT, Thailand 2007 2nd International Course in Yeast Systems Biology, Göteborg, Sweden   Metabolic Engineering and Functional Genomics, DTU, Denmark 2008 3rd International Course in Yeast Systems Biology, Göteborg, Sweden Grants, Awards and Prizes 1998 University-wide Fellow, UGA, Athens, GA 2001 US Department of Energy Bio-based Industrial Fellow 2006 HC Ørsted Fellow 2007 Lundbeckfonden grant (DKK 111880)